Rediscover Communication

I read an interesting article linked by Applekid's post last summer about how computer systems were designed by people with Asperger Syndrome for people with Asperger Syndrome, that the nature of the way computers operate and the way that they are operated shows an obvious bias toward people of that mindset. The question I have is, how else would it be done? There are physical realities that have to guide the process (hardware), but how would a system designed from a more empathic mindset work?
WOULD it work? :)
"Kmart sucks"- Rainman